| 摘要 |
<p>Pyrazolopyridine compounds of the general formula (1) or pharmaceutically acceptable salts thereof act specifically on Edg-5, which is sphingosine-1-phosphate receptor, and thus are useful as fibrosis remedies: (1) wherein R?1, R2 and R3¿ are each C¿1-8? alkyl or the like; R?4¿ is hydrogen or the like; R?5 and R6¿ are each independently hydrogen, C¿1-8? alkyl, C1-6 alkoxy, halogeno, or the like; X is NH-, -O-, -CH2-, or the like; Y is NH- or the like; Z is CO- or the like; W is NH- or the like; and A is aryl, heteroaryl, or the like.</p> |
