发明名称 TREATMENT AND PREVENTION OF CARDIAC INSULIN RESISTANCE ASSOCIATED CONDITIONS
摘要 A method for the treatment or prophylaxis of cardiac insulin resistance or conditions associated with cardiac insulin resistance, in humans or non-huma n mammals, which method comprises the administration of an effective, non-toxi c and pharmaceutically acceptable amount of PPARy agonist, such as Compound (I ), or a pharmaceutically acceptable derivative thereof. Conditions associated with cardiac insulin resistance are: microvascular angina, atherosclerosis a nd congestive heart failure. Compounds include rosiglitazone, troglitazone, englitazone and pioglitazone.
申请公布号 CA2436116(A1) 申请公布日期 2001.12.20
申请号 CA20002436116 申请日期 2000.06.16
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 NATHWANI, AMEET
分类号 A61K45/00;A61K31/426;A61K31/427;A61K31/4439;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P43/00;(IPC1-7):A61K31/426;A61K31/443 主分类号 A61K45/00
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