DNA chip and reactive electrode

摘要

A nucleic acid detective means composed of an electrode and plural peptide nucleic acids which are fixed onto the electrode via covalent bonding is favorably employed for electrochemically detecting complementary DNA fragments The covalent bonding between the electrode and the peptide nucleic acids are favorably produced by the reaction between a reactive hydrogen-containing group attached to the peptide nucleic acid and a vinylsulfonyl group or a reactive precursor thereof attached to the electrode.