RECOMBINANT MULTIVALENT MALARIAL VACCINES AGAINST <i>PLASMODIUM VIVAX</i>

摘要

Recombinant proteins are provided which comprise peptides derived from different stages in the life cycle of the parasite Plasmodium vivax. The proteins are useful as reagents and, when combined with a pharmaceutically acceptable vehicle or carrier, are useful as vaccines against the malarial parasite Plasmodium vivax. Genetic constructs used to produce these recombinant protein vaccines are also described. In addition, antibodies to these recombinant proteins are provided which are useful for the detection and measurement of peptides derived from different stages in the life cycle of the parasite Plasmodium vivax.