发明名称 |
Preparation of s,s and r,s amino acid isosteres |
摘要 |
The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S- diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity. |
申请公布号 |
EP1050532(A3) |
申请公布日期 |
2001.12.19 |
申请号 |
EP20000109083 |
申请日期 |
2000.05.03 |
申请人 |
AEROJET FINE CHEMICALS LLC |
发明人 |
MALIK, ASLAM A.;CLEMENT, TODD E.;PALANDOKEN, HASAN;ROBINSON, JAMES III;STRINGER, JOY A. |
分类号 |
C07C213/00;C07C215/08;C07D263/20;C07D301/27;C07D303/36 |
主分类号 |
C07C213/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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