| 发明名称 |
COMPOSITIONS AND METHODS FOR CASPASE-INDUCED APOPTOSIS |
| 摘要 |
This invention provides methods and compositions for caspase-induced apoptosis. Chimeric proteins are provided that target cells in which apoptosis is to be induced. The chimeric proteins of this invention activate endogenous caspase or provide caspase units that cause cell death. Methods are provided for the use of the chimeric proteins of this invention for <i>in vivo</i> and <i>ex vivo</i> therapies to treat pathological conditions.
|
| 申请公布号 |
WO0143694(A3) |
申请公布日期 |
2001.12.13 |
| 申请号 |
WO2000US34554 |
申请日期 |
2000.12.18 |
| 申请人 |
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.;SHIRWAN, HAVAL |
发明人 |
SHIRWAN, HAVAL |
| 分类号 |
C12N15/09;A61K35/26;A61K38/00;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K14/47;C12N5/06;C12N9/50;C12N9/64;(IPC1-7):C12P21/06;C07K14/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
