发明名称 Compositions and methods for producing and using homogenous neuronal cell transplants
摘要 Methods of treating individuals suspected of suffering from diseases, conditions or disorders of the Central Nervous System which comprise implanting stable, homogeneous post-mitotic human neurons into the individual's brain are disclosed. Methods of treating individuals suspected of suffering from injuries, diseases, conditions or disorders characterized by nerve damage which comprise implanting stable, homogeneous post-mitotic human neurons at or near a site of said nerve damage. Pharmaceutical compositions comprising stable, homogeneous post-mitotic human neurons and a pharmaceutically acceptable medium are disclosed. Methods of generating non-human animal models of human CNS diseases, conditions or disorders which comprise implanting stable, homogeneous post-mitotic human neurons into the brain of a non-human animal are disclosed. Non-human animals comprising stable, homogeneous post-mitotic human neurons implanted in their brain are disclosed.
申请公布号 US2001052136(A1) 申请公布日期 2001.12.13
申请号 US20010862204 申请日期 2001.05.22
申请人 LEE VIRGINIA M. Y.;TROJANOWSKI JOHN Q. 发明人 LEE VIRGINIA M. Y.;TROJANOWSKI JOHN Q.
分类号 A01K67/027;A61K35/12;A61K35/30;A61K48/00;C12N5/0793;(IPC1-7):A01K67/027 主分类号 A01K67/027
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