Process for producing 2-O-Alpha-D-Glucopyranosyl-L-ascorbic acid in high content

摘要

Disclosed is a process for producing a high alpha G-AA content product, which comprises the steps of: contacting a solution as a material solution, containing alpha G-AA, L-ascorbic acid, and a saccharide(s), with an anion exchange resin packed in a column to adsorb the alpha G-AA and L-ascorbic acid on the anion exchanger; washing the anion exchanger with water to remove the saccharide (s) therefrom; feeding to the column an aqueous solution, as an eluent, of an acid and/or a salt with a concentration of less than 0.5 N to fractionate a fraction rich in 2-0- alpha -D-glucopyranosyl-L-ascorbic acid and a fraction rich in L-ascorbic acid; and collecting the former fraction.