| 发明名称 |
Retroviral vectors produced by producer cell lines resistant to lysis by human serum |
| 摘要 |
Retroviral vectors which are resistant to inactivation by human serum. The retroviral vectors are produced in a cell line which is resistant to lysis by human serum, such cell lines including the HOS, Mv-1-Lu, HT1080, TE671, and human 293 cell lines, as well as cell lines derived therefrom. Such retroviral vectors are especially useful as in vivo gene delivery vehicles.
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| 申请公布号 |
US6329199(B1) |
申请公布日期 |
2001.12.11 |
| 申请号 |
US19990374746 |
申请日期 |
1999.08.13 |
| 申请人 |
PENSIERO MICHAEL;COLLINS MARY K. L.;COSSET FRANCOIS-LOIC;TAKEUCHI YASUHIRO;WEISS ROBIN A. |
发明人 |
PENSIERO MICHAEL;COLLINS MARY K. L.;COSSET FRANCOIS-LOIC;TAKEUCHI YASUHIRO;WEISS ROBIN A. |
| 分类号 |
C12N15/09;A61K31/70;A61K35/76;A61K38/00;A61K38/21;A61K38/22;A61K38/28;A61K38/46;A61K39/395;A61K48/00;C07H21/04;C12N5/10;C12N7/00;C12N15/64;C12N15/867;(IPC1-7):C12N15/867 |
主分类号 |
C12N15/09 |
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