| 发明名称 |
Mutant PLK protein and gene encoding the same |
| 摘要 |
<p>A mutant Plk protein having a mutation in C-terminal domain thereof specified by amino acid residues of from 439 to 603 of amino acid sequence of wild-type Plk protein wherein said mutation decreases affinity with Hsp90 protein, and a gene encoding said mutant Plk protein are provided. A method for detecting an abnormal cell which comprises the step of detecting the mutant Plk protein or the gene encoding the protein is also provided. <IMAGE></p> |
| 申请公布号 |
EP1160326(A1) |
申请公布日期 |
2001.12.05 |
| 申请号 |
EP20010113036 |
申请日期 |
2001.05.29 |
| 申请人 |
RIKEN |
发明人 |
OSADA, HIROYUKI;SIMIZU, SIRO |
| 分类号 |
G01N33/50;C07K14/47;C12N9/12;C12N15/09;C12N15/12;C12N15/54;C12Q1/04;C12Q1/68;G01N33/15;G01N33/574;G01N33/68;(IPC1-7):C12N15/54 |
主分类号 |
G01N33/50 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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