发明名称 |
ERYTHROPOIETIN (EPO) PEPTIDES AND ANTIBODIES DIRECTED AGAINST THESE |
摘要 |
Erythropoietin (EPO) peptides and the use thereof for preparing epitope-specific anti-EPO antibodies are described. Also described are corresponding anti-EPO antibodies which take the form of polyclonal antibodies (antisera) or of monoclonal antibodies. These antibodies are suitable for purifying EPO, EPO derivatives or EPO peptides. The epitope-specific anti-EPO antibodies according to the invention can also be used for the detection of EPO and, in particular, for the epitope- specific detection of EPO. Additionally described are anti-idiotype antibodies which imitate a receptor region of EPO. Finally, pharmaceuticals which contain the said EPO peptides, anti-EPO antibodies or anti-idiotype antibodies, and diagnostic aids for the detection of EPO or of anti-EPO antibodies, are described.
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申请公布号 |
CA2021912(C) |
申请公布日期 |
2001.11.27 |
申请号 |
CA19902021912 |
申请日期 |
1990.07.25 |
申请人 |
BEHRINGWERKE AKTIENGESELLSCHAFT |
发明人 |
FIBI, MATHIAS;STUBER, WERNER |
分类号 |
G01N33/53;A61K38/00;A61K38/22;A61K39/395;A61K45/00;A61K49/00;A61P7/00;A61P7/06;C07K1/22;C07K7/08;C07K14/00;C07K14/505;C07K14/52;C07K16/00;C07K16/22;C07K16/42;C12N5/10;C12N15/02;C12N15/16;C12P21/02;C12P21/08;C12R1/91;G01N33/577;G01N33/74;(IPC1-7):C12P21/08;C07K7/04;A61K38/18 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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