| 摘要 |
Carbohydrate derivatives comprising a trisaccharide unit having the general formula I (see formula I) in which R is alkyl, aryl, or aralkyl: Q is alkyl, aryl, aralkyl, or SO3-: A and B are independently selected from hydrogen, alkyl, aryl, aralkyl, or a carbohydrate group; and the charged moieties are compensated by counter- ions. The carbohydrate derivatives of this invention possess anti-thrombotic activity, and especially they have potent anti-X a activity without activating thrombin via anti-thrombin-III (AT-III) and smooth muscle cell proli- feration inhibiting activity.
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