| 摘要 |
The preparation of cyclohexanones of formula (I) by hydrogenation of phenols of formula (II) in the presence of a palladium-on-charcoal (Pd-C) catalyst at 100-250 degrees C and 1-20 bar hydrogen (H2) is carried out in the presence of linear, branched or cyclic alkanes (III), with a boiling point > 70 degrees C at normal pressure. as solvent; in which R<1-5> = hydrogen (H), hydroxyl (OH), 1-10C alkyl, 3-6C cycloalkyl, 6-10C aryl, 6-10C aryl-CH2-, 6-10C aryl-O-, 1-10C alkoxy, 3-8C cycloalkoxy, mono- or di-(1-4 C alkyl)-amino, 1-4C acylamino, COOR<6> or R<7>-CH2-; R<6> = H or 1-4C alkyl; R<7> = OH, 1-4C alkoxy or mono- or di-(1-4 C alkyl)-amino. |
