PHARMACEUTICAL SOLID COMPOSITIONS AND PROCESS FOR THE PRODUCTION OF MOUTH DISSOLVING TABLETS

摘要

Solid pharmaceutical compositions containing various ingredients for the production of Mouth dissolving Tablets (MDT) are described. Also described herewith the process using the said compositions which when processed as per the process described herein produce tablets containing active pharmaceutical ingredients preferably the Non Steroid Analgesics. The compositions are prepared by spraying the granulating solution on the dry-mix consisting of polyalcohol and the active ingredient in fluidized bed dryer containing such spraying facility. The tablets prepared using the compositions described using the process show remarkable fast disintegration in the mouth cavity without any action like chewing, even in absence of any carrier like water or hot/cold drinks. The tablets being rapid disintegrating can be easily administered to the aged, children and non-cooperating patients.