发明名称 Amine compounds and combinatorial libraries comprising same
摘要 The present invention provides monocyclic, bicyclic and oligomeric amine compounds with at least two sites of diversity. These compounds are formed from monocyclic scaffolds which can be cyclized to form bicyclic amine scaffolds. These can then be reacted with building blocks to form the amine compounds of the invention. This invention further provides libraries or monocyclic, bicyclic and oligomeric amine compounds. Also provided are methods for preparing monocyclic, bicyclic and oligomeric amine compounds and libraries thereof. The present invention also provides pharmaceutical compositions of the monocyclic, bicyclic and oligomeric amine compounds.
申请公布号 US6316626(B1) 申请公布日期 2001.11.13
申请号 US19980148732 申请日期 1998.09.04
申请人 ISIS PHARMACEUTICALS, INC. 发明人 SWAYZE ERIC EDWARD;SPRANKLE KELLY G.
分类号 C07B61/00;C07D243/08;C07D487/04;C12Q1/18;G01N33/68;(IPC1-7):C07D29/44 主分类号 C07B61/00
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