发明名称 POLY(ADP-RIBOSE)POLYMERASE INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a compound effective as a medicament for the therapy or prophylaxis of disease caused by the sthenia of poly(ADP-ribose)polymerase. SOLUTION: A poly(ADP-ribose)polymerase inhibitor comprises a compound represented by formula (1) [wherein -X1-X2- is a group represented by the formula -C(=O)-N(R7)- or -C(R8)=N-, or the like; R7 is H, a substituted or unsubstituted alkyl group, or the like; R8 is a substituted or unsubstituted alkyl group, or the like; ring Q is a group represented by the formula (2) to (4); and R1 to R6 are each H, a substituted or unsubstituted alkyl group, or the like] or a prodrug thereof, or at least one of their medicinally permissible salts.
申请公布号 JP2001302515(A) 申请公布日期 2001.10.31
申请号 JP20000116579 申请日期 2000.04.18
申请人 SUMITOMO PHARMACEUT CO LTD 发明人 ONO YUKIHIRO;OTANI KENICHI;AINO HIROSHI;SAJI KITARO
分类号 C07D239/96;A61K31/517;A61K31/519;A61P1/00;A61P3/10;A61P7/10;A61P9/06;A61P9/10;A61P17/00;A61P19/02;A61P25/14;A61P25/16;A61P25/28;A61P27/00;A61P31/04;A61P35/00;A61P43/00;C07D487/04;(IPC1-7):A61K31/517 主分类号 C07D239/96
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