摘要 |
PROBLEM TO BE SOLVED: To provide a compound effective as a medicament for the therapy or prophylaxis of disease caused by the sthenia of poly(ADP-ribose)polymerase. SOLUTION: A poly(ADP-ribose)polymerase inhibitor comprises a compound represented by formula (1) [wherein -X1-X2- is a group represented by the formula -C(=O)-N(R7)- or -C(R8)=N-, or the like; R7 is H, a substituted or unsubstituted alkyl group, or the like; R8 is a substituted or unsubstituted alkyl group, or the like; ring Q is a group represented by the formula (2) to (4); and R1 to R6 are each H, a substituted or unsubstituted alkyl group, or the like] or a prodrug thereof, or at least one of their medicinally permissible salts.
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