A method for isolating and purifying ⁹⁰Y from ⁹⁰strontium in multi-curie quantities

摘要

The invention relates to a process for separating and purifying multi-curie quantities 90Y of sufficient chemical and radiochemical purity suitable for use in medical applications without a series of 90Sr selective extraction chromatographic columns while minimizing loss of radioactive 90Sr parent and waste stream. The process includes dissolving a nitrate salt of an original 90Sr stock solution in H2O creating a strontium nitrate solution; acidifying the strontium nitrate solution containing 90Y with concentrated nitric acid; evaporating the strontium nitrate solution; filtering or centrifuging strontium nitrate solution to separate crystalline 90Sr nitrate salt from the solution; evaporating the remaining 90Y enriched supernate to dryness; dissolving the remaining 90Y enriched supernate in a strong acid; passing the solution through an yttrium selective extraction chromatographic column; rinsing the yttrium selective extraction chromatographic column with strong acid; and eluting yttrium from yttrium selective extraction column with strong acid.