发明名称 |
Human suppressor tRNA oligonucleotides and methods of use for same |
摘要 |
Novel synthetic suppressor tRNA have been provided which provide read-through of internal nonsense mutations, or which can site-specifically alter translation of transcribed sequences. Uses of the same are also provided in genetic engineering protocols including gene therapy treatment of diseases such as Xeroderma pigmentosum.
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申请公布号 |
US6309830(B1) |
申请公布日期 |
2001.10.30 |
申请号 |
US19990229212 |
申请日期 |
1999.01.13 |
申请人 |
HUMAN GENE THERAPY RESEARCH INSTITUTE |
发明人 |
PANCHAL REKHA G.;LINK, JR. CHARLES J. |
分类号 |
C12N15/09;A61K31/7105;A61K48/00;A61P17/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/22;C12N15/11;H04B10/24;(IPC1-7):A61K48/00;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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