发明名称 THERAPEUTIC USES FOR MESENCHYMAL STROMAL CELLS
摘要 Human mesenchymal stromal cells can be induced to differentiate into oligodendrocytes and neurons, respectively. For these cell types, therefore, MSCs can be a therapeutic source, either in vitro or in vivo, in the context of treating pathologies of the central nervous system which are characterize d by neuron loss, such as Parkinson's disease, Alzheimer's disease and stroke, as well as head trauma, or by dysfunction in ganglioside storage or demyelinization, such as Tay-Sachs disease, G1 gangliosidosis, metachromatic leukodystrophy, and multiple sclerosis.
申请公布号 CA2406196(A1) 申请公布日期 2001.10.25
申请号 CA20012406196 申请日期 2001.04.12
申请人 CHILDREN'S HOSPITAL OF PHILADELPHIA 发明人 BEESLEY, JACQUELINE S.;GRINSPAN, JUDITH;COYLE, ANDREW J.;TENNEKOON, GIHAN
分类号 C12N15/09;A61K35/12;A61K48/00;A61L27/00;A61P25/00;A61P25/28;C12N5/0775;C12N5/10;(IPC1-7):A61K35/12;C12N5/08;C12N5/06 主分类号 C12N15/09
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