Modified alpha2,3-sialyltransferase gene and process for producing alpha2,3-sialyltransferase and complex saccharide containing sialic acid

摘要

By using a microorganism having a gene obtained by modifying the base sequence of alpha 2,3-sialyltransferase gene originating in a microorganism belonging to the genus Haemophilus, alpha 2,3-sialyltransferase can be produced in a large amount. Moreover, a complex saccharide containing sialic acid can be economically produced in a large amount by bringing a microorganism producing the above-described enzyme with CMP-NeuAc and a receptor complex saccharide in an aqueous medium.