Microfluidic devices and systems incorporating cover layers

摘要

The present invention provides microfluidic devices (100) that comprise a body structure comprising at least a first microscale channel network (114) disposed therein. The body structure has a plurality of ports (106) disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also includes a cover layer (200) comprising a plurality of apertures (206) disposed through the cover layer. The cover layer (200) is mated with the body structure whereby each of the apertures (206) is aligned with a separate one of the plurality of ports. The devices also optionally include conductive coatings and membranes. The invention additionally provides methods of controlling the delivery of a composition of material into a microfluidic device (100).