| 摘要 |
PROBLEM TO BE SOLVED: To provide a new method excellent in practicality for producing an optically active 1-(benzofuran-2-yl)-2-propylaminopentane derivative useful as a medicine, especially an antipsychotic agent, an antidepressant agent, an antiparkinson agent and an antialzheimer agent. SOLUTION: This method for producing the optically active 1-(benzofuran-2- yl)-2-propylaminopentane derivative with high purity, in high selectivity and high yield by an extremely simple operation without using a special catalyst, or the like, comprises using an optically active aziridine compound or an optically active amide compound, capable of being chiral-pool synthesized from a commercial amino acid. |
