| 摘要 |
<p>The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is known ('known GPCRs'), and most particularly to mutated (non-endogenous) versions of the knowns GPCRs for use, most preferably in screening assays for the direct identification of candidate compounds as inverse agonists, agonists and partial agonists.</p> |
