发明名称 ESTROGEN AGONIST/ANTAGONIST METABOLITES
摘要 This invention relates to compounds that are mammalian metabolites of (-)-ci s- 6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydronaphthale ne- 2-ol. The compounds of the invention can be used as standards for analytical assays or as intermediates for the further chemical synthesis or biosynthesi s of chemical entities. The invention also relates to pharmaceutical compositions for the treatment of disease and methods of treating disease.</ SDOAB>
申请公布号 CA2405070(A1) 申请公布日期 2001.10.18
申请号 CA20012405070 申请日期 2001.03.19
申请人 PFIZER PRODUCTS INC., 发明人 JOHNSON, KIM ANNE;EGGLER, JAMES FREDERICK;DAY, WESLEY WARREN;PRAKASH, CHANDRA AGGARWAL
分类号 C07D295/08;A61K31/195;A61K31/197;A61K31/40;A61P3/04;A61P3/06;A61P3/10;A61P5/10;A61P5/28;A61P9/10;A61P11/00;A61P13/08;A61P15/00;A61P15/10;A61P17/00;A61P17/08;A61P17/10;A61P17/14;A61P19/02;A61P19/10;A61P25/26;A61P25/28;A61P27/12;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07C229/12;C07D207/12;C07D207/26;C07D207/27;C07D295/092;C07H15/203;(IPC1-7):C07D295/08 主分类号 C07D295/08
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