发明名称 ReL1A BINDING INHIBITOR, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF
摘要 Human RelA-associated inhibitor (RAI) comprising 351 amino acid, process for producing it, cDNA encoding it, fragment capable of hybridizing selectively to the cDNA sequence, plasmid for expression and duplication comprising the cDNA, host cell transformed with the plasmid, antibody against the polypeptide, pharmaceutical composition comprising the polypeptide or the antibody against it and method for diagnosis of diseases using the antibody against the RAI. RAI of the invention is capable of binding to p65, which is a submit of transcription factor NF kappa B, therefore, it is thought to be useful for treatment and/or prevention of various diseases.
申请公布号 EP1146054(A1) 申请公布日期 2001.10.17
申请号 EP19990973038 申请日期 1999.12.02
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 OKAMOTO, TAKASHI
分类号 A61K38/00;C07K14/47;C12N15/12;C12P21/08;(IPC1-7):C07K14/47;C12N5/10;C12P21/02;C07K16/18 主分类号 A61K38/00
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