发明名称 |
Methods of using (-) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
摘要 |
<p>A composition comprising (-) cisapride, or a pharmaceutically acceptable salt thereof, wherein the composition is for eliciting an antiemetic effect in a human by administering an amount thereof sufficient to alleviate nausea and vomiting whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride; or the composition is for treating a condition caused by gastrointestinal motility dysfunction in a human by administering an amount thereof sufficient to alleviate said condition whilst being insufficient to cause adverse side-effects associated with the administration of racemic cisapride, or while achieving a higher bioavailability than achieved with racemic cisapride, and wherein the (-)-cisapride or pharmaceutically acceptable salt thereof comprises at least 90% by weight of the total amount of cisapride in the composition.</p> |
申请公布号 |
EP1145715(A2) |
申请公布日期 |
2001.10.17 |
申请号 |
EP20010113441 |
申请日期 |
1993.07.06 |
申请人 |
SEPRACOR INC. |
发明人 |
GREY, NANCY M.;YOUNG, JAMES W |
分类号 |
C07D211/62;A61K31/445;A61K31/4468;A61P1/00;A61P1/08;A61P1/10;A61P1/14;(IPC1-7):A61K31/446 |
主分类号 |
C07D211/62 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|