发明名称 |
(1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION |
摘要 |
New (1-adamantylamino)pyridines of formula (2) wherein substituents R1, R2, R3, R4 or R5 are adamantylamino group, hydrogen atom, methyl group or halogen atom, the molecule of formula (2) containing one adamantylamino group and a substituent or substituents being methyl groups or halogen atoms at a position different from an-ortho position to the amino group, and the method of preparation of the new compounds. Studies have shown that these compounds stimulate secretion of TNF- alpha in some neoplastic cell lines. |
申请公布号 |
WO0174778(A1) |
申请公布日期 |
2001.10.11 |
申请号 |
WO2001PL00029 |
申请日期 |
2001.04.03 |
申请人 |
FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII;KAZIMIERCZUK, ZYGMUNT;LASEK, WITOLD;SIKORSKA, AGATA |
发明人 |
KAZIMIERCZUK, ZYGMUNT;LASEK, WITOLD;SIKORSKA, AGATA |
分类号 |
A61K31/4402;A61K31/4406;C07D213/74 |
主分类号 |
A61K31/4402 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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