发明名称 COMPOSITION FOR THE PREVENTION AND/OR TREATMENT, IN NEWBORN BABIES, OF THE EFFECTS OF COMPLICATIONS DURING CHILDBIRTH
摘要 A selective inhibitor of neuronal nitric oxide synthase (nNOS) and of inducible nitric oxide synthase (iNOS), which does not substantially inhibit endothelial nitric oxide synthase (eNOS), can be effectively used for the treatment, in human or other mammalian neonates, of the effects of complications during childbirth. Such effects include perinatal asphyxia and hypoxia-ischemia. A very useful example of such a selective inhibitor is 2-iminobiotin.
申请公布号 WO0174351(A1) 申请公布日期 2001.10.11
申请号 WO2001NL00266 申请日期 2001.03.30
申请人 UNIVERSITAIR MEDISCH CENTRUM;PEETERS, CACHA, MARIE, PETRONELLE, CATHERINE, DOROTHEE;GROENENDAAL, FLORIS;VAN BEL, FRANK 发明人 PEETERS, CACHA, MARIE, PETRONELLE, CATHERINE, DOROTHEE;GROENENDAAL, FLORIS;VAN BEL, FRANK
分类号 A61K31/00;A61K31/155;A61K31/17;A61K31/195;A61K31/198;A61K31/415;A61K31/4164;A61K31/4188;A61P9/10;A61P39/06;(IPC1-7):A61K31/195 主分类号 A61K31/00
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