| 发明名称 |
SIGMA RECEPTOR LIGANDS AND THEIR MEDICAL USES |
| 摘要 |
The present invention is based on the finding that sigma receptor ligands can modulate endothelial cell proliferation and/or survival, and hence control angiogenesis, and in particular that sigma receptor ligand antagonists can be used to inhibit angiogenesis and so treat conditions such as psoriasis, diabetic retinopathy and cancer. Exemplary compounds include IPAG and rimcazole.
|
| 申请公布号 |
WO0174359(A1) |
申请公布日期 |
2001.10.11 |
| 申请号 |
WO2001GB01495 |
申请日期 |
2001.04.02 |
| 申请人 |
SPRUCE, BARBARA;ECCLES, SUZANNE;DEXTER, MICHAEL |
发明人 |
SPRUCE, BARBARA;ECCLES, SUZANNE;DEXTER, MICHAEL |
| 分类号 |
A61K31/00;A61K31/155;A61K31/439;A61K31/445;A61K31/496;A61K45/00;A61P1/04;A61P9/00;A61P9/10;A61P15/00;A61P17/00;A61P17/06;A61P27/00;A61P27/02;A61P35/00;A61P35/04;A61P43/00;G01N33/15;G01N33/50;(IPC1-7):A61K31/495 |
主分类号 |
A61K31/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
