发明名称 HYDROXYPHENYL-PIPERIDIN-4-YLIDENE-METHYL-BENZAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN
摘要 Compounds of general formula (I) where R1 is selected from any one of phenyl , pyridinyl, thienyl, furanyl, imidazolyl, triazolyl and thiazolyl; where each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently b e further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iod o. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in th e management of pain.
申请公布号 CA2404386(A1) 申请公布日期 2001.10.11
申请号 CA20012404386 申请日期 2001.03.30
申请人 ASTRAZENECA AB 发明人 BROWN, WILLIAM;WALPOLE, CHRISTOPHER
分类号 C07D401/06;A61K31/4465;A61K31/4523;A61K31/4525;A61K31/4535;A61K31/4545;A61P1/00;A61P25/00;A61P25/02;A61P25/04;C07D211/68;C07D211/70;C07D405/06;C07D409/06;C07D417/06;(IPC1-7):C07D401/06;A61K31/452 主分类号 C07D401/06
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