| 发明名称 |
Process for preparing aryl piperazinyl-heterocyclic compounds |
| 摘要 |
<p>A process for preparing a compounds of the formula <CHEM> or a pharmaceutically acceptable acid addition salt thereof, which comprises reacting a piperazine of the formula <CHEM> with an alkyl halide containing compound of the formula <CHEM> in water with a reagent to neutralize the hydrohalic acid and heating the mixture under conditions which are suitable to effect the coupling of said piperazine with said alkyl halide containing compound.</p> |
| 申请公布号 |
EP0584903(B1) |
申请公布日期 |
2001.10.04 |
| 申请号 |
EP19930303576 |
申请日期 |
1993.05.07 |
| 申请人 |
PFIZER INC. |
发明人 |
BUSCH, FRANK R.;ALLEN, DOUGLAS;BOWLES, PAUL;DIROMA, SABETO A.;GODEK, DENNIS M. |
| 分类号 |
A61K31/47;A61K31/427;A61K31/495;A61K31/496;A61P25/02;A61P25/18;A61P25/20;C07D209/04;C07D215/16;C07D215/38;C07D235/04;C07D249/18;C07D263/54;C07D277/62;C07D295/02;C07D403/06;C07D403/12;C07D413/12;C07D417/12;C07D417/14;(IPC1-7):C07D417/12;C07D209/34 |
主分类号 |
A61K31/47 |
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