Novel water soluble c-ring analogues of 20 (s)-camptothecin
摘要
<CHEM> Novel water-soluble C-ring analogues of 20(s)-camptothecin having general formula (1). All the compounds of formula (1) are prepared from the compounds of general formula (2) having 20(s)-chiral carbon where R<1> to R<5> have the meaning given above. The compounds of formula (1) possess potent anti-cancer and anti-viral properties. The invention also provides an alternate process for the preparation of known C-5 substituted compounds of formula (1).
申请公布号
EP1138682(A1)
申请公布日期
2001.10.04
申请号
EP20010115319
申请日期
1997.04.22
申请人
DR. REDDY'S RESEARCH FOUNDATION;REDDY-CHEMINOR, INC.