摘要 |
<p>A compound of formula (I) wherein: R1 and R2, which may be the same or different, are CF3; halogen; CN; branched or unbranched C1-8 alkyl; branched or unbranched C1-8 alkenyl; C3-8 cycloalkyl; C1-8 alkoxy; C1-4 alkyloxyalkyl; C1-8 alkylthioalkyl; C1-8 dialkylamino; C1-4 dialkylaminoalkyl; CO2R4 aryl or hetorocyclyl connected to the imidazole in any position that makes a stable bond which aryl or heterocyclyl is optionally substituted; L is -NHC(O)-; -NHC(O)O-; -NHC(S)-; -NH-; -NHC(O)NH-; -NHC(S)HN-; -NHCH2-; -NHCH(R5)-; R3 is C¿1-8? alkyl; C1-8 alkyloxy; C1-8 alkylthio; C1-8 alkylamino; C1-4 alkoxyalkyl; C1-4 alkylthioalkyl; C1-4 alkylaminoalkyl; C1-4 dialkylalkylaminoalkyl; carbocyclyl or heterocyclyl; or a pharmaceutically acceptable derivative thereof.</p> |