发明名称 |
Detection of immunological memory, t-cell conjugates for pathology imaging and therapy |
摘要 |
A method for detecting prior exposure of an individual mammal's immune system to an antigen associated with a pathological process comprises exposing T-cells to a complex antigen mixture, and detecting a pre-existing T-cell specificity for an unknown antigen in said complex antigen mixture. Labelled T-cells are then used to image the site of the pathology and T-cells conjugated to a cytotoxic agent or precursor are used to treat the pathology. |
申请公布号 |
AU5472201(A) |
申请公布日期 |
2001.10.03 |
申请号 |
AU20010054722 |
申请日期 |
2001.03.22 |
申请人 |
TORSANA ONCOLOGY SYSTEMS APS |
发明人 |
HANS JORGEN GOTTLIEB GUNDERSEN;JESPER ZEUTHEN;STEEN JUEL NIELSEN |
分类号 |
G01N33/50;A61P35/00;C12N5/06;C12N5/08;C12Q1/02;G01N33/569 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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