Method for treatment of neurodegenerative diseases

摘要

The invention relates to a method of identifying an agent useful in treatment of a neurodegenerative disease by assaying for capacitative calcium entry in cells treated with the agent. The invention also relates to a method of identifying an agent which inhibits capacitative calcium entry-linked gamma-secretase activity by assaying for capacitative calcium entry in cells treated with the agent. The invention is further related to a method of treatment of a neurodegenerative disease by administering an agent which is capable of potentiating capacitative calcium entry activity.