BMP-9 COMPOSITIONS AND METHODS FOR INDUCING DIFFERENTIATION OF CHOLINERGIC NEURONS
摘要
BMP-9 compositions and methods for their use are disclosed. The BMP-9 compositions act as a differentiating factor for the cholinergic phenotype of CNS neurons. The compositions may be used in the treatment of diseases and disorders caused by degeneration and/or malfunctioning of cholinergic neurons.
申请公布号
WO0117547(A3)
申请公布日期
2001.09.27
申请号
WO2000US24555
申请日期
2000.09.07
申请人
GENETICS INSTITUTE, INC.;TRUSTEES OF BOSTON UNIVERSITY
发明人
BLUSZTAJN, JAN, KRZYSZTOF;LOPEZ-COVIELLA, IGNACIO;KRAUSS, RAUL;THIES, R., SCOTT