摘要 |
There is provided di-substituted iminoheterocyclic compounds of the formula (I) in which, A is optionally substituted alkyl group, optionally substitute d aryl group or optionally substituted heterocyclic group; X is oxygen atom, sulfur atom, carbon atom or nitrogen atom;the group -X-Y- represents optionally substituted alkylene or cyclic alkenylene bond; and B1 and B2 are , hydrogen atom, optionally substituted alkyl group, optionally substituted ar yl group or optionally substituted heterocyclic group, independent from each other, or a pharmaceutically acceptable salt thereof. These compounds have good affinity for (.alpha.4.beta.2 nicotinic acetylcholine receptors and activate the same to thereby exert a preventive or therapeutic effect on cerebral dysfunction.
|