发明名称 DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS
摘要 There is provided di-substituted iminoheterocyclic compounds of the formula (I) in which, A is optionally substituted alkyl group, optionally substitute d aryl group or optionally substituted heterocyclic group; X is oxygen atom, sulfur atom, carbon atom or nitrogen atom;the group -X-Y- represents optionally substituted alkylene or cyclic alkenylene bond; and B1 and B2 are , hydrogen atom, optionally substituted alkyl group, optionally substituted ar yl group or optionally substituted heterocyclic group, independent from each other, or a pharmaceutically acceptable salt thereof. These compounds have good affinity for (.alpha.4.beta.2 nicotinic acetylcholine receptors and activate the same to thereby exert a preventive or therapeutic effect on cerebral dysfunction.
申请公布号 CA2364268(A1) 申请公布日期 2001.09.27
申请号 CA20012364268 申请日期 2001.03.21
申请人 SUNTORY LIMITED 发明人 TANI, YOSHIHIRO;AKABANE, MINAKO;IMOTO, MASAHIRO;IWANAMI, TATSUYA
分类号 A61K31/4427;A61K31/4439;A61K31/4523;A61K31/4545;A61K31/506;A61K31/5355;A61P1/00;A61P9/10;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P29/00;A61P43/00;C07D213/74;C07D401/06;C07D401/14;C07D413/14;C07D417/06;C07D417/14;(IPC1-7):C07D401/06;C07D411/06;C07D411/14 主分类号 A61K31/4427
代理机构 代理人
主权项
地址