发明名称 |
Chemokine receptor antagonists and methods of use therefor |
摘要 |
Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula:and physiologically acceptable salts thereof.
|
申请公布号 |
US6288084(B1) |
申请公布日期 |
2001.09.11 |
申请号 |
US19990235111 |
申请日期 |
1999.01.21 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
LULY JAY R.;NAKASATO YOSHISUKE;OHSHIMA ETSUO |
分类号 |
C07D491/107;A61K31/4406;A61K31/4418;A61K31/4427;A61K31/443;A61K31/444;A61K31/4545;A61K31/496;A61K31/497;A61K31/501;A61K31/506;A61K31/5355;A61K31/537;A61K31/5377;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P31/18;A61P37/06;A61P37/08;A61P43/00;C07D213/36;C07D213/38;C07D401/06;C07D401/14;C07D405/14;C07D409/14;C07D471/10;C07D491/10;C07D495/10;C07D498/10;(IPC1-7):A61K31/454;A61K31/438 |
主分类号 |
C07D491/107 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|