发明名称 Method of treating lymphoproliferative syndrome
摘要 Lymphoproliferative syndrome, including such diseases as malignant lymphoma, chronic lymphocytic leukemia, Hodgkin's lymphoma, and non-Hodgkin's lymphoma, is treated in human patients by the administration by a pharmacologically effective mode or route of an essentially pure opiate receptor antagonist, typified by Naltrexone and Naloxone, exerting substantially higher blocking action for Mu opiate receptor sites than against Delta opiate receptor sites at a low dose concentration which produces therapeutic results corresponding to those obtained by the administration of Naltrexone at a low dosage level in the range of 1.0 mg. to 10 mg. and at which Delta receptor blocking activity is at most small and Mu receptor blocking activity is significant and most preferably substantially exclusive. Naltrexone is suitable for oral administration and is preferred.
申请公布号 US6288074(B1) 申请公布日期 2001.09.11
申请号 US19990439987 申请日期 1999.11.15
申请人 BIHARI BERNARD 发明人 BIHARI BERNARD
分类号 A61K31/44;(IPC1-7):A61K31/44 主分类号 A61K31/44
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