| 摘要 |
Uridylic acid is obtained by culturing a bacterium belonging to Brevibacterium ammoniagenes under aerobic at 20 DEG to 40 DEG C. and at a pH of 5.5 to 9.0 in a fermentation medium therefor which, in addition to the normal constituents thereof, contains uracil or a derivative thereof which yields uracil in situ. The uracil may be present at the commencement of the fermentation or added during the course of culturing. Generally, the amount of uracil used is from about 0.1 gram to about 10 grams per litre of medium. The fermentation may be carried out in a shaking culture or in submerged culture with shaking and aeration. The fermentation medium used contains a carbon source such as carbohydrates; a nitrogen source, inorganic substances and nitrogen-containing natural products. Examples are given for the production of the compound.
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