<p>The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promotor or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promotor or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.</p>
申请公布号
EP1130106(A1)
申请公布日期
2001.09.05
申请号
EP20000200728
申请日期
2000.03.01
申请人
RIJKSUNIVERSITEIT TE GRONINGEN
发明人
DE LEIJ, LOU FRANCISCUS MARIA HUBERTUS;MCLAUGHLIN, PAMELA MARIJKE JANE;RUITERS, MARCEL HERMAN JOSEF;HARMSEN, MARTIN CONRAD;VAN DER MOLEN, HENK;TERPSTRA, PETER;DOKTER, WILLEM HENDRIK ABRAHAM