发明名称 NEW GENE AND ITS USE
摘要 PROBLEM TO BE SOLVED: To provide a protein that is useful as a medicine for preventing and treating a disease such as hypoglycemia, and to provide a DNA encoding the protein, wherein the protein and the DNA are useful as agents for screening a compound inhibiting the binding of the protein with IRAP (insulin responsive aminopeptidase) or GLUT4 (glucose transporter 4), wherein the compound is useful as a medicine for preventing and treating a disease such as melitemia and diabetes. SOLUTION: A new protein, a DNA encoding the protein, a method for producing the protein, a medicine containing the protein, an antibody against the protein, a method for screening a compound inhibiting the binding of the protein with IRAP, and a compound obtained by the screening, are provided.
申请公布号 JP2001238685(A) 申请公布日期 2001.09.04
申请号 JP20000385386 申请日期 2000.12.19
申请人 TAKEDA CHEM IND LTD 发明人 TOJO HIDEAKI;KATAYAMA NOZOMI;KAKIMOTO MOHACHI
分类号 G01N33/50;A61K31/711;A61K38/55;A61K45/00;A61K48/00;A61P3/08;A61P3/10;A61P43/00;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;C12Q1/37;C12R1/865;C12R1/91;G01N33/15;G01N33/53 主分类号 G01N33/50
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