发明名称 |
Vinyl-ACA purification process |
摘要 |
A process for purification of vinyl-ACA of formulafrom a mixture of vinyl-ACA and 7-ADCA of formulais provided. The process comprises a) producing a mixture of a salt of vinyl-ACA and a salt of 7-ADCA in a solvent in which the salt of 7-ADCA has a higher solubility than the salt of vinyl-ACA, and b) subjecting the mixture to crystallization to obtain a precipitate of the salt of vinyl-ACA. A process of purifying vinyl-ACA from a mixture of vinyl-ACA and 7-ADCA via chromatography, particularly adsorption chromatography is also provided.
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申请公布号 |
US6284888(B1) |
申请公布日期 |
2001.09.04 |
申请号 |
US20000567623 |
申请日期 |
2000.05.09 |
申请人 |
BIOCHEMIE GESELLSCHAFT M.B.H. |
发明人 |
LUDESCHER JOHANNES;VEIT WERNER |
分类号 |
A61K31/00;A61K31/545;A61K31/546;A61P31/00;A61P31/04;B01D9/02;C07D501/00;C07D501/12;C07D501/18;C07D501/22;(IPC1-7):C07D501/12 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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地址 |
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