| 发明名称 |
HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE |
| 摘要 |
<p>Novel inhibitors of protein farnesyltransferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.</p> |
| 申请公布号 |
GR3035936(T3) |
申请公布日期 |
2001.08.31 |
| 申请号 |
GR20010400790T |
申请日期 |
2001.05.25 |
| 申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BOLTON, GARY, LOUIS;HODGES, JOHN, COOKE;WILSON, MICHAEL, WILLIAM |
| 分类号 |
A61K31/415;A61K38/00;A61K38/55;A61P9/00;A61P35/00;A61P43/00;C07D233/54;C07D233/64;C07K1/02;C07K1/04;C07K5/078;C07K5/097;(IPC1-7):C07K5/078;A61K38/05;A61K38/06 |
主分类号 |
A61K31/415 |
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