METHOD AND APPARATUS FOR PREPARING TAXOL USING SUPERCRITICAL FLUID FROM SOURCE MATERIALS

摘要

Methods for isolating taxol and derivatives thereof with high purity are described. The methods include a supercritical fluid and a cosolvent extraction step, a liquid-liquid separation step, and a column chromatography step. An apparatus for isolating Taxol and derivatives thereof that allows the method steps to be performed online also is described.