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发明名称 USE OF IL-18 INHIBITORS
摘要 The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheumatoid arthritis. In addition to this, the invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of inflammatory bowel diseases, in particular of Crohn's disease and ulcerative colitis.
申请公布号 WO0162285(A1) 申请公布日期 2001.08.30
申请号 WO2001EP01867 申请日期 2001.02.20
申请人 APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;YEDA RESEARCH AND DEVELOPMENT COMPANY LTD;CHVATCHKO, YOLANDE;DINARELLO, CHARLES;PLATER-ZYBERK, CHRISTINE;VAN DEVENTER, SANTER;RUBINSTEIN, MENACHEM;NOVICK, DANIELA;KIM, SOO-HYUN 发明人 CHVATCHKO, YOLANDE;DINARELLO, CHARLES;PLATER-ZYBERK, CHRISTINE;VAN DEVENTER, SANTER;RUBINSTEIN, MENACHEM;NOVICK, DANIELA;KIM, SOO-HYUN
分类号 C12N15/09;A61K31/00;A61K35/12;A61K38/00;A61K38/17;A61K38/21;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P1/16;A61P19/02;A61P19/08;A61P25/32;A61P29/00;A61P31/12;A61P37/00;A61P37/02;A61P43/00;C07K16/24;C12N15/63;(IPC1-7):A61K39/395 主分类号 C12N15/09
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