发明名称 |
ANTAGONISTIC SELECTIVE BINDING AGENTS OF OSTEOPROTEGERIN BINDING PROTEIN |
摘要 |
Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and m ay be used to prevent or treat conditions relating to loss of bone mass. Nuclei c acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provid ed. |
申请公布号 |
CA2400929(A1) |
申请公布日期 |
2001.08.30 |
申请号 |
CA20012400929 |
申请日期 |
2001.02.23 |
申请人 |
AMGEN INC. |
发明人 |
HITZ, ANNA;DESHPANDE, RAJENDRA V.;SULLIVAN, JOHN KEVIN;BOYLE, WILLIAM J. |
分类号 |
C12N15/09;A61K38/22;A61K39/395;A61K45/00;A61P3/14;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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