发明名称 ANTAGONISTIC SELECTIVE BINDING AGENTS OF OSTEOPROTEGERIN BINDING PROTEIN
摘要 Selective binding agents of osteoprotegerin binding protein (OPGbp) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to OPGbp and m ay be used to prevent or treat conditions relating to loss of bone mass. Nuclei c acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provid ed.
申请公布号 CA2400929(A1) 申请公布日期 2001.08.30
申请号 CA20012400929 申请日期 2001.02.23
申请人 AMGEN INC. 发明人 HITZ, ANNA;DESHPANDE, RAJENDRA V.;SULLIVAN, JOHN KEVIN;BOYLE, WILLIAM J.
分类号 C12N15/09;A61K38/22;A61K39/395;A61K45/00;A61P3/14;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/08 主分类号 C12N15/09
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