METHODS AND COMPOSITIONS FOR THE IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF HUMAN CANCERS
摘要
The present invention is directed to the identification of markers that can be used to determine the sensitivity of cancer cells to a therapeutic agent. The present invention is also directed to the identification of therapeutic targets. Nucleic acid arrays were used to determine the level of expression of sequences (genes) found in 60 different solid tumor cancer cell lines selected from the NCI 60 cancer cell line series. Expression analysis was used to identify markers associated with sensitivity to certain chemotherapeutic agents.
申请公布号
WO0161050(A2)
申请公布日期
2001.08.23
申请号
WO2001US05301
申请日期
2001.02.16
申请人
MILLENNIUM PREDICTIVE MEDICINE, INC.
发明人
ROTH, FREDERICK, P.;VAN HUFFEL, CHRISTOPHE;WHITE, JAMES, V.;SHYJAN, ANDREW, W.