发明名称 |
NOVEL PYRAZINE DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES OR THE SALTS AND INTERMEDIATES FOR THE PREPARATION OF BOTH |
摘要 |
Pyrazine derivatives of the general formula [1] or salts thereof exhibit excellent antiviral activities and are useful as remedies for viral infectio n. In the formula [1], each symbol is as defined in the description. Further, fluoropyrazine derivatives of the general formula [2] or salts thereof are useful as intermediates not only for the preparation of the compounds [1], b ut for industrial production of fluoropyrazinecarboxamide derivatives such as 6 - fluoro-3-hydroxy-2-pyrazinecarboxamide having an antiviral effect. In the formula [2] each symbol is as defined in the description. |
申请公布号 |
CA2398620(A1) |
申请公布日期 |
2001.08.23 |
申请号 |
CA20012398620 |
申请日期 |
2001.02.14 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
EGAWA, HIROYUKI;YONEZAWA, KENJI;FURUTA, YOUSUKE;HAMAMOTO, SHOICHI;SUGITA, JUN;UEHARA, SAYURI |
分类号 |
A61P31/12;C07H19/04;(IPC1-7):C07H19/04;C07D405/04;C07D241/24;A61K31/496;A61K31/706 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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