发明名称 Production process for polymeric micelle charged therein with drug and polymeric micelle composition
摘要 Provided are a production process for a polymeric micelle which is stable and has a high drug content and a composition containing such polymeric micelle. Disclosed are a production process for a polymeric micelle, comprising the steps of dissolving a drug and a specific copolymer in a water non-miscible organic solvent to prepare a solution, mixing the resulting solution with water to form an O/W type emulsion and then slowly volatilizing the organic solvent from the solution, and a polymeric micelle composition charged therein with a water-scarcely soluble drug, which can be obtained by the above production process.
申请公布号 US2001014354(A1) 申请公布日期 2001.08.16
申请号 US20010778901 申请日期 2001.02.08
申请人 NANOCARRIER CO., LTD. 发明人 YOKOYAMA MASAYUKI;HONZAWA EIICHI;OGAWA YASUAKI
分类号 A61K47/30;A61K9/10;A61K9/107;A61K9/127;A61K9/51;A61K31/337;A61K31/4545;A61K31/519;A61K31/704;(IPC1-7):A61K9/50;B01J13/02 主分类号 A61K47/30
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